There is no downtime after a PRP therapy procedure, and you can resume your normal activities immediately. However, you should avoid any strenuous activity and follow your doctor’s instructions for wound care and medication. You may experience some mild side effects, such as swelling, bruising, redness, or irritation at the injection site, but these usually go away within a few days. You should contact your doctor if you have any signs of infection, allergic reaction, or serious complications.